Detection of Anti-viral Drug Riamilovir and Herbicides in Aqueous Media by Using Pyrene-based Fluorescent Chemosensors

Abstract

Two ethyleneglycol esters of 1-pyrene carboxylic acid were studied as chemosensors for the fluorescence “turn-off” detection of two nitro-containing analytes, such as antiviral drug Riamilovir (Triazavirin ®) and herbicidal agent dinitro-ortho-cresol (DNOC). In both cases the dramatic fluorescence quenching was observed with quenching constants as high as 3·104 M-1 and limits of detection (LOD) as low as 100 ppb.

Keywords

• covid-19
• riamilovir (triazavirin ®)
• dnoc
• detection in aqueous media
• chemical sensors
• pyrene-based fluorophores
• fluorescence quenching