Toxins (Oct 2022)

Quantitative Proteomic Analysis of Zearalenone Exposure on Uterine Development in Weaned Gilts

  • Xinglin Liu,
  • Zengchun Wang,
  • Yanping Jiang,
  • Libo Huang,
  • Xuejun Yuan,
  • Yang Li,
  • Ning Jiao,
  • Weiren Yang,
  • Shuzhen Jiang

DOI
https://doi.org/10.3390/toxins14100692
Journal volume & issue
Vol. 14, no. 10
p. 692

Abstract

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The aim of this study was to explore the effect of zearalenone (ZEA) exposure on uterine development in weaned gilts by quantitative proteome analysis with tandem mass spectrometry tags (TMT). A total of 16 healthy weaned gilts were randomly divided into control (basal diet) and ZEA3.0 treatments groups (basal diet supplemented with 3.0 mg/kg ZEA). Results showed that vulva size and uterine development index were increased (p p p p p p < 0.01). This study sheds new light on the molecular mechanism of ZEA in the uterine development of gilts.

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