Journal of Cardiovascular and Thoracic Research (Feb 2021)

Coagulopathy: Another side effect of coronavirus infection

  • Fatemeh Sadoughi,
  • Parisa Maleki Dana,
  • Jamal Hallajzadeh,
  • Zatollah Asemi,
  • Mohammad Ali Mansournia,
  • Bahman Yousefi

DOI
https://doi.org/10.34172/jcvtr.2020.59
Journal volume & issue
Vol. 13, no. 1
pp. 15 – 22

Abstract

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Recently, coronavirus disease 2019 (COVID-19) has been considered as a major health problem around the globe. This severe acute respiratory syndrome has a bunch of features, such as high transmission rate, which are adding to its importance. Overcoming this disease relies on a complete understanding of the viral structure, receptors, at-risk cells or tissues, and pathogenesis. Currently, researches have shown that besides the lack of a proper anti-viral therapeutic method, complications provided by this virus are also standing in the way of decreasing its mortality rate. One of these complications is believed to be a hematologic manifestation. Commonly, three kinds of coagulopathies are detected in COVID-19 patients: disseminated intravascular coagulation (DIC), pulmonary embolism (PE), and deep vein thrombosis (DVT). In this paper, we have reviewed the relation between these conditions and coronavirus-related diseases pathogenesis, severity, and mortality rate.

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