Data for the measurement of serum vitamin D metabolites in childhood acute lymphoblastic leukemia survivors
E. Delvin,
M. Boisvert,
M.-A. Lecours,
Y. Théorêt,
M. Kaufmann,
G. Jones,
E. Levy
Affiliations
E. Delvin
CHU Ste-Justine Research Centre, University of Montréal, Montréal, Canada; Department of Biochemistry, University of Montréal, Montréal, Canada; Corresponding author at: CHU Ste-Justine Research Centre, University of Montréal, Montréal, Canada.
M. Boisvert
CHU Ste-Justine Research Centre, University of Montréal, Montréal, Canada
M.-A. Lecours
CHU Ste-Justine Research Centre, University of Montréal, Montréal, Canada
Y. Théorêt
CHU Ste-Justine Research Centre, University of Montréal, Montréal, Canada; Clinical Pharmacology Unit, Department of Clinical Biochemistry, CHU Ste-Justine, University of Montréal, Montréal, Canada; Department of Pharmacology, University of Montréal, Montréal, Canada
M. Kaufmann
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Canada
G. Jones
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Canada
E. Levy
CHU Ste-Justine Research Centre, University of Montréal, Montréal, Canada; Department of Nutrition, University of Montréal, Montréal, Canada
This article describes data related to a companion research paper entitled “Vitamin D nutritional status and bone turnover biomarkers in childhood acute lymphoblastic leukemia (cALL) survivors.” (Delvin et al., submitted for publication) [1]. Various methods for the measurement of serum 25OHD3, the accepted biomarker for assessing vitamin D nutritional status, have been described (Le Goff et al., 2015; Jensen et al., 2016) [2,3]. This article describes a novel mass spectrometry-QTOF method for the quantification of circulating 25OHD3, 3-epi-25OHD3 and 24,25(OH)2D3. It provides the description of the extraction, chromatography and mass spectrometry protocols, a sample of mass spectra obtained from standards and extracted serum, and a comparison with another HPLC-MS/MS (Jensen et al., 2016) [3] method for the measurement of serum concentrations of 25OHD3.
