Frontiers in Endocrinology (Jul 2023)

Relationships between intra-pancreatic fat deposition and lifestyle factors: a cross-sectional study

  • Kento Mitsushio,
  • Megu Y. Baden,
  • Megu Y. Baden,
  • Sarasa Kato,
  • Akiko Niki,
  • Harutoshi Ozawa,
  • Harutoshi Ozawa,
  • Saori Motoda,
  • Chisaki Ishibashi,
  • Yoshiya Hosokawa,
  • Yukari Fujita,
  • Ayumi Tokunaga,
  • Takao Nammo,
  • Takao Nammo,
  • Junji Kozawa,
  • Junji Kozawa,
  • Iichiro Shimomura

DOI
https://doi.org/10.3389/fendo.2023.1219579
Journal volume & issue
Vol. 14

Abstract

Read online

AimsThe excess deposition of intra-pancreatic fat deposition (IPFD) has been reported to be associated with type 2 diabetes, chronic pancreatitis, and pancreatic ductal adenocarcinoma. In the current study, we aimed to identify a relationship between lifestyle factors and IPFD.Materials and methods99 patients admitted to the Osaka University Hospital who had undergone abdominal computed tomography were selected. We evaluated the mean computed tomography values of the pancreas and spleen and then calculated IPFD score. Multiple regression analyses were used to assess the associations between IPFD score and lifestyle factors.ResultsFast eating speed, late-night eating, and early morning awakening were significantly associated with a high IPFD score after adjusting for age, sex, diabetes status and Body Mass Index (p=0.04, 0.01, 0.01, respectively).ConclusionThe current study has elucidated the significant associations of fast eating speed, late-night eating, and early morning awakening with IPFD.

Keywords