ADMET and DMPK (Sep 2018)

Block relevance (BR) analysis and polarity descriptors in property-based drug design

  • Giuseppe Ermondi,
  • Giulia Caron

DOI
https://doi.org/10.5599/admet.532
Journal volume & issue
Vol. 6, no. 3
pp. 215 – 224

Abstract

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Block Relevance (BR) analysis is a tool to interpret QSPR/PLS models which can provide the information content of any physicochemical determinant used in property-based drug discovery; its application for the characterization of experimental polarity descriptors is discussed.

Keywords