A Contemporary Analysis of Mental Well-being Among Living Donor Kidney Applicants

Swee-Ling Levea, MD; Jai G. Prasadh, BS; Benjamin K. Wang, MD; Juan D. Salcedo-Betancourt, MD; Lauren Matevish, MD; Jorge Sanchez Vivaldi, MD; Sarah R. Lieber, MD, MSCR; Jigesh A. Shah, DO; Christine S. Hwang, MD; David Wojciechowski, DO; Parsia A. Vagefi, MD; Madhukar S. Patel, MD, MBA, ScM

doi:10.1097/TXD.0000000000001631

Transplantation Direct (Jun 2024)

A Contemporary Analysis of Mental Well-being Among Living Donor Kidney Applicants

Swee-Ling Levea, MD,
Jai G. Prasadh, BS,
Benjamin K. Wang, MD,
Juan D. Salcedo-Betancourt, MD,
Lauren Matevish, MD,
Jorge Sanchez Vivaldi, MD,
Sarah R. Lieber, MD, MSCR,
Jigesh A. Shah, DO,
Christine S. Hwang, MD,
David Wojciechowski, DO,
Parsia A. Vagefi, MD,
Madhukar S. Patel, MD, MBA, ScM

Affiliations

Swee-Ling Levea, MD: 1 Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Jai G. Prasadh, BS: 2 Division of Surgical Transplantation, University of Texas Southwestern Medical Center, Dallas, TX.
Benjamin K. Wang, MD: 2 Division of Surgical Transplantation, University of Texas Southwestern Medical Center, Dallas, TX.
Juan D. Salcedo-Betancourt, MD: 1 Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Lauren Matevish, MD: 2 Division of Surgical Transplantation, University of Texas Southwestern Medical Center, Dallas, TX.
Jorge Sanchez Vivaldi, MD: 2 Division of Surgical Transplantation, University of Texas Southwestern Medical Center, Dallas, TX.
Sarah R. Lieber, MD, MSCR: 1 Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Jigesh A. Shah, DO: 2 Division of Surgical Transplantation, University of Texas Southwestern Medical Center, Dallas, TX.
Christine S. Hwang, MD: 2 Division of Surgical Transplantation, University of Texas Southwestern Medical Center, Dallas, TX.
David Wojciechowski, DO: 1 Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Parsia A. Vagefi, MD: 2 Division of Surgical Transplantation, University of Texas Southwestern Medical Center, Dallas, TX.
Madhukar S. Patel, MD, MBA, ScM: 2 Division of Surgical Transplantation, University of Texas Southwestern Medical Center, Dallas, TX.

DOI: https://doi.org/10.1097/TXD.0000000000001631
Journal volume & issue: Vol. 10, no. 6
p. e1631

Abstract

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Background. Living donation is paramount for expanding the donor pool. The aim of this study was to assess changes over time in self-reported mental health of living donor kidney applicants in efforts to inform patient-centered discussions with potential donors. Methods. Kidney donor applications from 2017 through 2021 were compiled. Data included age, gender, race, ethnicity, applicant–recipient relationship, medical history, and medications. Trends over time were analyzed and post hoc analyses were performed. Results. During the study period, 2479 applicants to the living donor kidney program were evaluated; 73% of applicants were female individuals. More than half of applicants were not related to their intended recipient; this fraction increased from 46% in 2017 to 58% in 2021 (P < 0.01). A similar decline in family relations was not present among Black and Latino applicants. Of all applicants, 18% reported depression and 18% reported anxiety; 20% reported taking antidepressants or anxiolytics. Depression and anxiety increased 170% (P < 0.001) and 136% (P < 0.001) from 2018 to 2019, respectively; antidepressant and anxiolytic use rose 138% (P < 0.001) between 2018 and 2020. Conclusions. The profile of living donor applicants has changed in recent years, with approximately 1 in 5 requiring antidepressants or anxiolytics. Predonation counseling and postdonation monitoring are imperative to decrease adverse psychological outcomes for living donors.

Published in Transplantation Direct

ISSN: 2373-8731 (Online)
Publisher: Wolters Kluwer
Country of publisher: United States
LCC subjects: Medicine: Surgery
Website: http://journals.lww.com/transplantationdirect/Pages/default.aspx

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