Hypoglycemia and hyperglycemia: potential risks of polypragmasia in type 2 diabetes in hospital settings

Abstract

Chronic hyperglycemia imposes damage on a number of cell types and is strongly correlated with the variety of related complications such as eyes, kidneys, cardiovascular system etc. This fact implies pharmacological treatment. Some are metabolic neutral, some are apt to provoke hypoglycemia and/or hyperglycemia, invert pharmacological response. To take into account a potential role of treatment on glucose level is crucial for pharmacotherapy in patient with T2DM. Besides, some drugs may distort the meaning of lab tests.

Keywords

• polypragmasia
• hypoglycemia
• hyperglycemia
• diabetes mellitus type 2
• drug interactions