Journal of Arrhythmia (Aug 2017)

Clinical benefits of deep sedation with a supraglottic airway while monitoring the bispectral index during catheter ablation of atrial fibrillation

  • Satoru Hida, M.D.,
  • Masao Takemoto, M.D., Ph.D.,
  • Akihiro Masumoto, M.D., Ph.D.,
  • Takahiro Mito, M.D., Ph.D.,
  • Kazuhiro Nagaoka, M.D., Ph.D.,
  • Hiroshi Kumeda, M.D.,
  • Yuki Kawano, M.D.,
  • Ryota Aoki, M.D.,
  • Honsa Kang, M.D.,
  • Atsushi Tanaka, M.D., Ph.D.,
  • Atsutoshi Matsuo, M.D.,
  • Kiyoshi Hironaga, M.D., Ph.D.,
  • Teiji Okazaki, M.D., Ph.D.,
  • Kiyonobu Yoshitake, M.D.,
  • Kei-ichiro Tayama, M.D., Ph.D.,
  • Ken-ichi Kosuga, M.D., Ph.D.

DOI
https://doi.org/10.1016/j.joa.2017.04.001
Journal volume & issue
Vol. 33, no. 4
pp. 283 – 288

Abstract

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Background: Pulmonary vein antrum isolation (PVAI) under sedation has proven to be a useful strategy for catheter ablation of atrial fibrillation (AF). Methods: To evaluate the clinical benefits of respiratory management using supraglottic airways (SGAs) under deep sedation while monitoring the bispectral (BIS) index during the PVAI and the durations from admission to the catheterization room to starting the radiofrequency energy delivery (Time α), and from starting the radiofrequency energy delivery to completion of the PVAI (Time β), X-ray time, frequency of dislocations of the three-dimensional maps (D3DM), procedure-related complications, and proportion of an AF-free rate 15 months after the PVAI (PAFFR) in patients who received deep sedation without SGAs (Group A: n=48) and those with SGAs (Group B: n=51) were evaluated. Results: There were no significant differences in patient characteristics, Time α (77±3 versus 78±2 min; p=0.816), complications of cardiac tamponade (2% versus 2%; p=0.966), or PAFFR (81% versus 88%; p=0.313) between the two groups. However, the Time β (84±4 versus 67±3; p=0.001), X-ray time (53±2 versus 34±2; p<0.001), and minor complications of nasal bleeding (25% versus 0%; p=0.001) were significantly shorter and lower in Group B than in Group A, in accordance with a reduction in the hypoxia (15% versus 0%; p=0.007) and D3DM (31% versus 8%; p=0.003). Conclusions: These results may demonstrate the clinical benefits of deep sedation with SGAs while monitoring the BIS index without any hypoxia during PVAI in patients with AF.

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