Design of a Flow-through Polarographic Sensor Based on Metal Films for Determining N-nitrosodiethanolamine Levels in Rabbit Biological Fluids

Abstract

The construction and characterization of a flow-through polarographic detectorfor catalyzing the electroreduction of N-nitrosodiethanolamine (NDELA), is discussed. Theflow-through cell is equipped with a gold wire electrode (a thin mercury film deposited on agold substance). The response is evaluated with respect to substance diameter, length,concentration of modifying film, operating potential, supporting electrolyte and pH, andflow rate in the DC mode. The system allows the determination of N-nitrosodiethanolaminein rabbit biological fluids with relatively inexpensive equipment.

Keywords

• Flow-through polarographic detector
• thin-film modified metal electrode
• Nnitrosodiethanolamine
• rabbit biological fluids.