Forbes Tıp Dergisi (Apr 2021)

Castleman's Disease: Due to a Rare Intraabdominal Location

  • Mehmet Cihan Karacaoğlu,
  • Nursel Yurttutan,
  • Betül Kızıldağ,
  • Turgay Kara,
  • Sezen Koçarslan

DOI
https://doi.org/10.5222/forbes.2021.66376
Journal volume & issue
Vol. 2, no. 1
pp. 49 – 53

Abstract

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Castleman disease (CD) is a rare benign disease with unknown etiology. It is also called angiofollicular lymph node hyperplasia, giant lymph node hyperplasia, lymph node hamartoma, benign giant lymphoma. Histologically, it is classified as hyaline vascular and plasma cell variant, but rarely features of two types can coexist. Most of the cases with unisentric disease are hyaline vascular and most of the cases with multicentric disease are in plasma cell histological type. Although it is frequently located in thorax, it can be found throughout the body. Salivary glands, lungs, pancreas, larynx, parotid gland, meninges, and even limb muscles can be affected as extralymphatic spread. Since it is localized in the middle and anterior mediastinum in the thorax, it should be differentiated from mediastinal autoimmune and neoplastic diseases. In this case report, we aimed to present the radiological findings of a CD case with a rare intraabdominal location.

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