MODERN PRINCIPLES OF MANAGEMENT OF PATIENTS WITH RHEUMATOID ARTHRITIS

Abstract

The lecture presents the new EULAR clinical guidelines on the treatment of rheumatoid arthritis (RA) published this year. The new version of the recommendations is fully international, because for its creation, the largest group of experts in the history of the development of the EULAR recommendations was collected, including not only the representatives of the EU countries, but also Russia, Asia, North and South America. The main changes compared to the previous (2013) version are: approval of achieving sustainable remission as treatment goal; the possibility of changing the treatment schedule during the first 3 months, the feasibility of short-term use of medium and high doses of glucocorticoids; the possibility of using targeted synthetic (ts-) DMARDs (tofacitinib) as second-line drugs; the advantage of the combination of biologics and ts-DMARDs with synthetic (s-) DMARDs over monotherapy; the advantage of tocilizumab and ts-DMARDs over other drugs if necessary using in monotherapy.

Keywords

• rheumatoid arthritis
• treatment strategy
• clinical recommendations
• biological agents
• of janus kinases inhibitor