Establishment of induced pluripotent stem cell line SDPHi003-A from a healthy male donor

Yue Xi; Haiyan Zhang; Xiaomeng Yang; Dan Ai; Yi Liu; Wei Song

Stem Cell Research (Sep 2023)

Establishment of induced pluripotent stem cell line SDPHi003-A from a healthy male donor

Yue Xi,
Haiyan Zhang,
Xiaomeng Yang,
Dan Ai,
Yi Liu,
Wei Song

Affiliations

Yue Xi: First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong, China; Tumor Minimally Invasive Comprehensive Treatment Department, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Ji’nan 250021, China; Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China
Haiyan Zhang: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China
Xiaomeng Yang: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China
Dan Ai: Tumor Minimally Invasive Comprehensive Treatment Department, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Ji’nan 250021, China
Yi Liu: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China; Corresponding authors at: Tumor minimally invasive comprehensive treatment department, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Ji’nan 250021, China.
Wei Song: First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong, China; Tumor Minimally Invasive Comprehensive Treatment Department, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Ji’nan 250021, China; Corresponding authors at: Tumor minimally invasive comprehensive treatment department, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Ji’nan 250021, China.

Journal volume & issue: Vol. 71
p. 103160

Abstract

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Peripheral blood mononuclear cells (PBMCs) were derived from a 67-year-old Chinese male. We used non-integrating episomal vectors containing OCT4, SOX2, KLF4 and c-MYC to reprogram PBMCs into induced pluripotent stem cell (iPSCs). This iPSC line, SDPHi003-A, have a normal karyotype, expressed pluripotent markers and have the potential for trilineage differentiation. This iPSC line can be used as a control for disease modeling studies and contribute to the research exploring disease pathogenesis.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

About the journal