Open Life Sciences (Jun 2024)

First report of Nocardia wallacei infection in an immunocompetent patient in Zhejiang province

  • Pan Wei,
  • Zhuo Bingqian,
  • Wang Sumei,
  • Long Jieping,
  • Xu Wei,
  • Chen Mengyuan,
  • Hong Xin,
  • Ge Yumei

DOI
https://doi.org/10.1515/biol-2022-0891
Journal volume & issue
Vol. 19, no. 1
pp. 13 – 20

Abstract

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Nocardiosis is an infectious disease caused by Nocardia spp., mainly affecting immunocompromised hosts. Nocardia infection is not common; especially Nocardia wallacei infection is even rarer. The patient, female, 61 years old, farmer, has been working in the field for a long time and has normal immune function. Her main clinical manifestation was persistent back pain. Chest-enhanced computed tomography showed pulmonary inflammation. Rare pathogen Nocardia wallacei was detected in alveolar lavage fluid using matrix-assisted laser destructive ionization time-of-flight mass spectrometry. She received treatment with linezolid and was discharged after her condition improved.

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