Biosensors (Dec 2022)

Recent Advances in Nanotechnology for the Management of <i>Klebsiella pneumoniae</i>–Related Infections

  • Mahmood Barani,
  • Hadis Fathizadeh,
  • Hassan Arkaban,
  • Davood Kalantar-Neyestanaki,
  • Majid Reza Akbarizadeh,
  • Abduladheem Turki Jalil,
  • Reza Akhavan-Sigari

DOI
https://doi.org/10.3390/bios12121155
Journal volume & issue
Vol. 12, no. 12
p. 1155

Abstract

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Klebsiella pneumoniae is an important human pathogen that causes diseases such as urinary tract infections, pneumonia, bloodstream infections, bacteremia, and sepsis. The rise of multidrug-resistant strains has severely limited the available treatments for K. pneumoniae infections. On the other hand, K. pneumoniae activity (and related infections) urgently requires improved management strategies. A growing number of medical applications are using nanotechnology, which uses materials with atomic or molecular dimensions, to diagnose, eliminate, or reduce the activity of different infections. In this review, we start with the traditional treatment and detection method for K. pneumoniae and then concentrate on selected studies (2015–2022) that investigated the application of nanoparticles separately and in combination with other techniques against K. pneumoniae.

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