Stargadt’s disease in two Nigerian siblings

Abstract

Tunji S Oluleye, Akinsola Sunday Aina, Tarela Frederick Sarimiye, Segun Isaac Olaniyan Retinal and Vitreous Unit, University College Hospital, Ibadan, Nigeria Abstract: Stargardt’s disease is an inherited macular dystrophy that is transmitted in an autosomal recessive or dominant pattern. The disorder is typically characterized by impairment of central vision, with onset around the first 10–20 years of life. Stargardt’s disease is rare in sub-Saharan Africa. This is probably the first reported case in the subregion. We present two siblings with the disease. Presentation, pathophysiology, and management modalities are discussed. Keywords: Stargardt’s disease, macular dystrophy, retinal, Nigerians