Clinicopathological Spectrum of COVID-19

Abstract

Objective: To analyse the clinicopathological spectrum of COVID-19 among 2000 patients. Study Design: Cross-sectional study. Place and Duration of Study: Combined Military Hospital, Abbottabad Pakistan, from Apr to Jun 2020. Methodology: The study included 2000 patients who came to CMH Abbottabad to seek medical attention during the first wave of the COVID-19 pandemic. Age, gender, contact history, history of foreign travel, clinical features, comorbid conditions and results of SARS-CoV-2 PCR were observed. Results: From 2000 cases, 1442(72%) were males, and 558(28%) were females. The mean age was 35.02±13.00 years, and 1275(63.8%) cases were from the 3rd to fourth decade of life. 900(45%) of the cases had a contact history with a COVID-19 patient, whereas only 4(0.2%) had a history of foreign travel. 1854(93.0%) of the cases were asymptomatic, whereas only 48(2.4%) presented with fever and cough, the most common symptoms. Only 26(1.3%) cases had associated comorbid conditions, and 263(13.0%) cases showed positive PCR results. The statistical association was found to be significant among age groups, gender, contact history and results of SARS-CoV-2 PCR,(p-value< 0.001). Conclusion: This study provides an overall view of the COVID-19 pandemic, which has grasped the globe within no time.Efficient preventive and control measures are mandatory, in addition to early identification and diagnosis, to overcome the infection.

Keywords

• Clinicopathological
• COVID-19
• SARS-CoV-2 PCR