Particle Image Velocimetry for in vitro characterization of Paravalvular Leakage of TAVR-sealing concepts

Abstract

Paravalvular leakage (PVL), defined as the leakage between the aortic annulus and a transcatheter aortic valve replacement (TAVR), is verifiably associated with short- and long-term clinical outcome, especially with increased mortality. Therefore, with the ambition to reduce or even prevent PVL of next generation TAVR, it is necessary to extend the hemodynamic understanding of PVL.

Keywords

• transcatheter aortic valve
• hydrodynamic testing
• particle image velocimetry
• paravalvular leakage