DETECTION OF IMMUNOGLOBULINS, ANTIBODIES TO HEAT-SHOCK PROTEINS AND IL-8 CYTOKINE IN SALIVA FROM THE PATIENTS WITH CHRONIC PERIODONTAL DISEASES

Abstract

Examination of the patients with chronic generalized periodontitis revealed a sufficient increase in all immunoglobulin classes, i.e., IgG, IgM, IgA, sIgA, as well as increased IL-8 concentration in their salivary samples. Emergence of antibodies to heat-shock proteins suggests a pathogenetic role of chaperon-like proteins in development of periodontal diseases.

Keywords

• heat-shock proteins
• immunity
• immunoglobulin
• periodontitis