Nature Communications (Dec 2017)
Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans
- Ananyo Choudhury,
- Michèle Ramsay,
- Scott Hazelhurst,
- Shaun Aron,
- Soraya Bardien,
- Gerrit Botha,
- Emile R. Chimusa,
- Alan Christoffels,
- Junaid Gamieldien,
- Mahjoubeh J. Sefid-Dashti,
- Fourie Joubert,
- Ayton Meintjes,
- Nicola Mulder,
- Raj Ramesar,
- Jasper Rees,
- Kathrine Scholtz,
- Dhriti Sengupta,
- Himla Soodyall,
- Philip Venter,
- Louise Warnich,
- Michael S. Pepper
Affiliations
- Ananyo Choudhury
- Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand
- Michèle Ramsay
- Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand
- Scott Hazelhurst
- Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand
- Shaun Aron
- Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand
- Soraya Bardien
- Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University
- Gerrit Botha
- Computational Biology Division, Department of Integrative Biomedical Sciences, IDM, University of Cape Town
- Emile R. Chimusa
- Division of Human Genetics, Department of Pathology, IDM, Faculty of Health Sciences, University of Cape Town
- Alan Christoffels
- South African MRC Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape
- Junaid Gamieldien
- South African MRC Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape
- Mahjoubeh J. Sefid-Dashti
- South African MRC Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape
- Fourie Joubert
- Department of Biochemistry and Genomics Research Institute, Centre for Bioinformatics and Computational Biology, University of Pretoria
- Ayton Meintjes
- Computational Biology Division, Department of Integrative Biomedical Sciences, IDM, University of Cape Town
- Nicola Mulder
- Computational Biology Division, Department of Integrative Biomedical Sciences, IDM, University of Cape Town
- Raj Ramesar
- Division of Human Genetics, Department of Pathology, IDM, Faculty of Health Sciences, University of Cape Town
- Jasper Rees
- Agricultural Research Council
- Kathrine Scholtz
- Department of Preclinical Sciences, School of Health Care Sciences, Faculty of Health Sciences, University of Limpopo
- Dhriti Sengupta
- Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand
- Himla Soodyall
- Division of Human Genetics, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand
- Philip Venter
- Department of Medical Sciences, School of Health Sciences, Faculty of Health Sciences, University of Limpopo
- Louise Warnich
- Department of Genetics, Stellenbosch University
- Michael S. Pepper
- Institute for Cellular and Molecular Medicine, Department of Immunology, Faculty of Health Sciences, University of Pretoria
- DOI
- https://doi.org/10.1038/s41467-017-00663-9
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 12
Abstract
African populations show a high level of genetic diversity and extensive regional admixture. Here, the authors sequence the whole genomes of 24 South African individuals of different ethnolinguistic origin and find substantive genomic divergence between two southeastern Bantu-speaking groups.
