Boosting the down-shifting luminescence of rare-earth nanocrystals for biological imaging beyond 1500 nm

Yeteng Zhong; Zhuoran Ma; Shoujun Zhu; Jingying Yue; Mingxi Zhang; Alexander L. Antaris; Jie Yuan; Ran Cui; Hao Wan; Ying Zhou; Weizhi Wang; Ngan F. Huang; Jian Luo; Zhiyuan Hu; Hongjie Dai

doi:10.1038/s41467-017-00917-6

Nature Communications (Sep 2017)

Boosting the down-shifting luminescence of rare-earth nanocrystals for biological imaging beyond 1500 nm

Yeteng Zhong,
Zhuoran Ma,
Shoujun Zhu,
Jingying Yue,
Mingxi Zhang,
Alexander L. Antaris,
Jie Yuan,
Ran Cui,
Hao Wan,
Ying Zhou,
Weizhi Wang,
Ngan F. Huang,
Jian Luo,
Zhiyuan Hu,
Hongjie Dai

Affiliations

Yeteng Zhong: CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China
Zhuoran Ma: Department of Chemistry, Stanford University
Shoujun Zhu: Department of Chemistry, Stanford University
Jingying Yue: Department of Chemistry, Stanford University
Mingxi Zhang: Department of Chemistry, Stanford University
Alexander L. Antaris: Department of Chemistry, Stanford University
Jie Yuan: Department of Chemistry, Stanford University
Ran Cui: Department of Chemistry, Stanford University
Hao Wan: Department of Chemistry, Stanford University
Ying Zhou: Department of Chemistry, Stanford University
Weizhi Wang: CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China
Ngan F. Huang: Stanford Cardiovascular Institute, Stanford University
Jian Luo: Department of Neurology and Neurological Sciences, School of Medicine, Stanford University
Zhiyuan Hu: CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China
Hongjie Dai: Department of Chemistry, Stanford University

DOI: https://doi.org/10.1038/s41467-017-00917-6
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 7

Abstract

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Fluorescence imaging in the near-infrared window between 1500–1700 nm (NIR-IIb window) offers superior spatial resolution and tissue penetration depth, but few NIR-IIb probes exist. Here, the authors synthesize rare earth down-converting nanocrystals as promising fluorescent probes for in vivo imaging in this spectral region.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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