Familial hypercholesterolemia: current status of the problem, treatment, and prevention

Abstract

Familial hypercholesterolemia is the most common hereditary disease characterized by an increase in low density lipoprotein cholesterol levels and the premature development of atherosclerosis-related cardiovascular diseases. Diagnosis and treatment of such patients are associated with certain difficulties. This review presents data on the prevalence of familial hypercholesterolemia, identification of patients with such a diagnosis, prevention of adverse cardiovascular events, and also discusses the appointment of lipid-lowering therapy.

Keywords

• гетерозиготная семейная гиперхолестеринемия
• холестерин липопротеинов низкой плотности
• гиполипидемическая терапия
• статины