Development and validation of a stability indicating UPLC-DAD method coupled with MS-TQD for ramipril and thymoquinone in bioactive SNEDDS with in silico toxicity analysis of ramipril degradation products

• Elzayat Ehab M.,
• Sherif Abdelrahman Y.,
• Shahba Ahmad Abdul-Wahhab,
• Kazi Mohsin,
• Alyahya Mohammed,
• Darwish Hany W.

Affiliations

Elzayat Ehab M.

Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

Sherif Abdelrahman Y.

Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

Shahba Ahmad Abdul-Wahhab

Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

Kazi Mohsin

Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

Alyahya Mohammed

Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

Darwish Hany W.

Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia