Thyroid Eye Disease and Glaucoma: A Cross-Sectional Study Comparing Clinical Characteristics and Disease Severity
Laura Andreea Ghenciu,
Alina Maria Șișu,
Emil Robert Stoicescu,
Alexandra-Ioana Dănilă,
Roxana Iacob,
Mihai-Alexandru Săndesc,
Ovidiu Alin Hațegan
Affiliations
Laura Andreea Ghenciu
Department of Functional Sciences, ‘Victor Babes’ University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania
Alina Maria Șișu
Department of Anatomy and Embriology, ‘Victor Babes’ University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania
Emil Robert Stoicescu
Field of Applied Engineering Sciences, Specialization Statistical Methods and Techniques in Health and Clinical Research, Faculty of Mechanics, ‘Politehnica’ University Timisoara, Mihai Viteazul Boulevard No. 1, 300222 Timisoara, Romania
Alexandra-Ioana Dănilă
Department of Anatomy and Embriology, ‘Victor Babes’ University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania
Roxana Iacob
Department of Anatomy and Embriology, ‘Victor Babes’ University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania
Mihai-Alexandru Săndesc
Department of Orthopedics and Traumatology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania
Ovidiu Alin Hațegan
Discipline of Anatomy and Embriology, Medicine Faculty, Vasile Goldis” Western University of Arad, Revolution Boulevard 94, 310025 Arad, Romania
Background and Objectives: This study investigates the relationship between thyroid eye disease (TED) and open-angle glaucoma (OAG), focusing on disease severity and clinical features. Materials and Methods: Conducted at the Timis County Emergency Clinical Hospital, the research included 106 patients, with 53 having both conditions and 53 having only OAG. Key metrics analyzed included intraocular pressure (IOP) using a Goldmann applanation tonometer, the retinal nerve fiber layer (RNFL) thickness, and optic nerve head (ONH) characteristics evaluated using optical coherence tomography (OCT). Results: Results indicated that patients with both TED and OAG experienced a 6.09% reduction in RNFL thickness and showed more rapid disease progression, with 48.35% having active TED. The mean IOP in TED patients was 27.5 ± 4.9 mmHg, which was similar to those with only OAG. Demographic factors, including age and gender, influenced the clinical course and disease severity. Conclusions: These findings underscore the importance of specialized monitoring and treatment strategies for patients with coexisting TED and OAG to prevent vision loss.
