Combined oral contraceptives with shortened hormone-free interval. Proven advantages of the therapy regime

Abstract

Objective: To determine the benefits of COC in the 26/2 mode compared with the traditional 21/7 in reducing the frequency of side effects. Main provisions. Side effects – the main cause of women’s refusals to take COCs – occur predominantly on days of taking pills without hormones due to a drop in estradiol levels. Reduction of the hormone-free COC interval (mode 26/2) reduces the frequency of headache and pelvic pain and other symptoms. Conclusion. COC, with regimen 26/2, may be a promising option for users who experience adverse symptoms.

Keywords

• combined oral contraceptives
• hormone-free interval
• 26/2 mode
• estradiol valerate
• dienogest