A clinical trial to evaluate the effect of Rasayana Avaleha during pregnancy W.S.R. to the fetal outcome

Abstract

Context: Health of the child depends directly on the environment and state of the fetus in intrauterine life. Supplementing Rasayana (rejuvenating and immunomodulatory) drugs in a Garbhini (pregnant women) provides positive maternal environment which helps the fetus to avoid or overcome diseases. Integrating Rasayana therapy in Garbhini Paricharya (antenatal care) not only benefits the pregnant lady but also the growing fetus in her womb. Aim: The aim of this study was to evaluate the efficacy of Rasayana Avaleha (RA) (Rasayana electuary) on fetal growth and development and its influence on fetal immune system. Setting and Design: Pregnant women fulfilling the inclusion criteria were selected from outpatient department of SDM Ayurveda Hospital, Udupi, Karnataka, for the study. The study was a randomized comparative clinical trial. Subjects and Methods: Trial group (n = 15) was administered RA 12 g twice a day with Ksheera (milk) as Anupana (adjuvant) in the 6 th and 7 th month of pregnancy. Control group (n = 15) was given calcium carbonate 500 mg and ferrous sulfate 200 mg once in a day during 6 th and 7 th month. Statistical Analysis: Paired t-test was used to compare within the group and unpaired t-test to compare between two groups. Results: With the overall effect of the study, fetus of the Rasayana group showed statistically significant increase in the ultrasonography parameters biparietal diameter and estimated fetal birth weight. Significant results were also seen in fetal birth weight and fetal immunoglobulin G when compared to control group. Conclusion: Administering RA in Garbhini (pregnancy) acts as a complete micronutrient providing positive effect on the fetal growth and nourishment and also in enhancing the fetal immunity level.

Keywords

• Garbhini Paricharya
• nutrition
• Rasayana
• Vyadhikshamatwa (immunity)