Modern Approaches to Rehabilitation of Patients with Osteoporotic Hip Fracture: the Role of Pathogenetic Therapy with Zoledronic Acid

Abstract

The article gives literature data systematic analysis (20 Russian and 47 foreign literature sources) on the issue of rehabilitation ofpatients with hip fracture (HF) against the background of osteoporosis (OP) and the role of pathogenetic therapy with zoledronic acidin the complex rehabilitation of such patients. Literature data testify to the high prevalence and medical and social significance ofosteoporotic HF in Russia and abroad. The need to develop effective methods for the rehabilitation of patients with OP is due to thedemand for patient’s life quality recovery in short terms, treatment cost reduction and death risk reduction, the highest during the firstyear after a pathological HF. The main objective of rehabilitation measures after osteoporotic HF is to reduce the likelihood of disabilityand death of the patient that is extremely high in the first months after the fracture – about 10% of elderly patients die in the first 3months after HF. The effectiveness of medical rehabilitation of patients with HF depends on the surgical treatment and mobilizationtime frames. Exercises are recommended to strengthen the muscles – knee extensors in the first 2–5 days after surgical treatment ofosteoporotic HF. After 3 weeks, progressive strength training should be included in rehabilitation programs to improve the functionalcapabilities of patients.Conclusion. Given the high risk of recurrent fractures in patients with osteoporosis undergoing rehabilitation after HF, the appointmentof pharmacological therapy for OP, primarily zoledronic acid at a dose of 5 mg once a year, should be a mandatory addition to physicaltherapy procedures.

Keywords

• osteoporosis
• hip fracture
• medical rehabilitation
• quality of life
• physical functioning
• zoledronic acid