Morphological characteristics of zone of titanium nickelide mesh prosthesis implantation after esophagocardiopexy in experiment

Abstract

The results of research using 20 rabbits are presented in the article. All animals underwent esophagocardiopexia by fixing nickel titanium mesh prosthesis to the diaphragm and the anterior wall of the stomach. The morphology of tissues in contact with the implant, histological and ultramicroscopic picture were assessed. Evaluation of foreign body reaction have demonstrated minimal degree of tissue reactions. After 6 weeks the changes of normal histological structure of the investigated organs were not detected. At the end of research period the collagen fibers formed the ordered structures around the metallic filaments. The obtained data have shown high biocompatibility of titanium nickelide mesh prosthesis and the low level of mesh-related complications.

Keywords

• esophagocardiopexy
• titanium nickelide
• mesh impant
• biocompatibility