Journal of Marine Medical Society (Jan 2022)
Short-term evaluation of renal transplantation complications: A single institute experience
Abstract
Introduction: Renal Transplant remains one of the pioneer branches of solid organ transplant and surgical complications can affect the outcome. Material and Methods: Present study was done to find out the incidence of surgical complications in Renal Transplant Recipients, their outcome, to compare it with contemporary studies and suggest remedial measures. It was Prospective non-randomized observational study conducted at tertiary centre. All patients who underwent live related or deceased donor transplant over two yrs were recruited. All relevant data was collected. Data were collected and put in a master chart in Microsoft Excel© format and statistical analysis was done using SPSS 17 software®. Student t test was used to compare data with published contemporary series and p value was calculated. Results: one hundred and forty-five cases including 31 (21%) deceased donor recipients were studied. Eleven (7.58%) had surgical complications. Two with arterial complications required graft nephrectomies and one with renal artery stenosis stented successfully. Higher incidence of arterial complications (2.06%) was noted as compared to contemporary studies (0.69%-1.3%) (p>.05) with higher incidence (3.2%) in deceased Donor recipients. No venous complications recorded (contemporary studies 0.15% - 0.55% incidence). One (0.68%) Ureteric stricture was reported, comparable to contemporary studies (0.27%-0.54%) (p>.05) and managed endoscopically. No uretric-vesical anastamosis leak recorded (contemporary studies 0% - 0.97% incidence). Four (2.75%) had Lymphorea, (Three deceased, one live donor) requiring Betadine instillation, significantly lower than contemporary studies (7.14%- 23%) (p<.05). Two (1.4%) had surgical site infection requiring secondary suturing, significantly lower than contemporary studies (3.2%- 15%) (<.05). One (0.68%) had stricture urethra managed conservatively, comparable to contemporary studies (0.83%-1.18%). Conclusion: Overall incidence of surgical complications is reducing. Complication rates are higher in Deceased Donor recipients.
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