Thoracic Cancer (Dec 2022)
Chinese expert consensus on the multidisciplinary management of pneumonitis associated with immune checkpoint inhibitor
- Wenxian Wang,
- Qian Wang,
- Chunwei Xu,
- Ziming Li,
- Zhengbo Song,
- Yongchang Zhang,
- Xiuyu Cai,
- Shirong Zhang,
- Bin Lian,
- Wen Li,
- Anwen Liu,
- Ping Zhan,
- Hongbing Liu,
- Tangfeng Lv,
- Liyun Miao,
- Lingfeng Min,
- Yu Chen,
- Jingping Yuan,
- Feng Wang,
- Zhansheng Jiang,
- Gen Lin,
- Xingxiang Pu,
- Chuangzhou Rao,
- Dongqing Lv,
- Zongyang Yu,
- Xiaoyan Li,
- Chuanhao Tang,
- Chengzhi Zhou,
- Congying Xie,
- Junping Zhang,
- Hui Guo,
- Qian Chu,
- Rui Meng,
- Jingxun Wu,
- Rui Zhang,
- Liping Wang,
- Youcai Zhu,
- Xiao Hu,
- Yanru Xie,
- Xinqing Lin,
- Jing Cai,
- Fen Lan,
- Huijing Feng,
- Lin Wang,
- Wang Yao,
- Xuefei Shi,
- Jianhui Huang,
- Huafei Chen,
- Yinbin Zhang,
- Pingli Sun,
- Bing Wan,
- Fei Pang,
- Zanmei Xu,
- Kai Wang,
- Yuanli Xia,
- Mingxiang Ye,
- Dong Wang,
- Qing Wei,
- Shuitu Feng,
- Jianya Zhou,
- Jiexia Zhang,
- Donglai Lv,
- Wenbin Gao,
- Jing Kang,
- Genhua Yu,
- Xianbin Liang,
- Chengtao Yu,
- Lin Shi,
- Nong Yang,
- Lin Wu,
- Zhuan Hong,
- Wei Hong,
- Meiyu Fang,
- Yiping Zhang,
- Yuanzhi Lu,
- Guansong Wang,
- Shenglin Ma,
- Lu Si,
- Wenfeng Fang,
- Yong Song
Affiliations
- Wenxian Wang
- Department of Chemotherapy Chinese Academy of Sciences University Cancer Hospital (Zhejiang Cancer Hospital) Hangzhou China
- Qian Wang
- Department of Respiratory Medicine Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine Nanjing China
- Chunwei Xu
- Institute of Cancer and Basic Medicine (ICBM) Chinese Academy of Sciences Hangzhou China
- Ziming Li
- Department of Shanghai Lung Cancer Center Shanghai Chest Hospital, Shanghai Jiao Tong University Shanghai China
- Zhengbo Song
- Department of Chemotherapy Chinese Academy of Sciences University Cancer Hospital (Zhejiang Cancer Hospital) Hangzhou China
- Yongchang Zhang
- Department of Medical Oncology, Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University Changsha China
- Xiuyu Cai
- Department of VIP Inpatient Sun Yet‐Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Guangzhou China
- Shirong Zhang
- Translational Medicine Research Center, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province Affiliated Hangzhou First People's Hospital, Cancer Center, Zhejiang University School of Medicine Hangzhou China
- Bin Lian
- Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Melanoma and Sarcoma Peking University Cancer Hospital and Institute Beijing China
- Wen Li
- Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine Second Affiliated Hospital of Zhejiang University School of Medicine, Cancer Center, Zhejiang University Hangzhou China
- Anwen Liu
- Department of Oncology Second Affiliated Hospital of Nanchang University Nanchang China
- Ping Zhan
- Department of Respiratory Medicine Affiliated Jinling Hospital, Medical School of Nanjing University Nanjing China
- Hongbing Liu
- Department of Respiratory Medicine Affiliated Jinling Hospital, Medical School of Nanjing University Nanjing China
- Tangfeng Lv
- Department of Respiratory Medicine Affiliated Jinling Hospital, Medical School of Nanjing University Nanjing China
- Liyun Miao
- Department of Respiratory Medicine Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing China
- Lingfeng Min
- Department of Respiratory Medicine Clinical Medical School of Yangzhou University, Subei People's Hospital of Jiangsu Province Yangzhou China
- Yu Chen
- Department of Medical Oncology Fujian Medical University Cancer Hospital and Fujian Cancer Hospital Fuzhou China
- Jingping Yuan
- Department of Pathology Renmin Hospital of Wuhan University Wuhan China
- Feng Wang
- Department of Internal Medicine, Cancer Center of PLA, Qinhuai Medical Area Affiliated Jinling Hospital, Medical School of Nanjing University Nanjing China
- Zhansheng Jiang
- Derpartment of Integrative Oncology Tianjin Medical University Cancer Institute and Hospital Tianjin China
- Gen Lin
- Department of Medical Oncology Fujian Medical University Cancer Hospital and Fujian Cancer Hospital Fuzhou China
- Xingxiang Pu
- Department of Medical Oncology, Lung Cancer, and Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University Changsha China
- Chuangzhou Rao
- Department of Radiotherapy and Chemotherapy, Hwamei Hospital University of Chinese Academy of Sciences Ningbo China
- Dongqing Lv
- Department of Pulmonary Medicine Taizhou Hospital of Wenzhou Medical University Taizhou China
- Zongyang Yu
- Department of Respiratory Medicine, The 900th Hospital of the Joint Logistics Team (The Former Fuzhou General Hospital) Fujian Medical University Fuzhou China
- Xiaoyan Li
- Department of Oncology Beijing Tiantan Hospital, Capital Medical University Beijing China
- Chuanhao Tang
- Department of Medical Oncology Peking University International Hospital Beijing China
- Chengzhi Zhou
- State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University (The First Affiliated Hospital of Guangzhou Medical University) Guangzhou China
- Congying Xie
- Department of Radiation Oncology First Affiliated Hospital, Wenzhou Medical University Wenzhou China
- Junping Zhang
- Department of Thoracic Oncology, Shanxi Academy of Medical Sciences Shanxi Bethune Hospital Taiyuan China
- Hui Guo
- Department of Medical Oncology The First Affiliated Hospital of Xi'an Jiaotong University Xi'an China
- Qian Chu
- Department of Oncology Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology Wuhan China
- Rui Meng
- Cancer Center, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China
- Jingxun Wu
- Department of Medical Oncology, The First Affiliated Hospital of Medicine Xiamen University Xiamen China
- Rui Zhang
- Department of Medical Oncology Cancer Hospital of China Medical University Shenyang China
- Liping Wang
- Department of Oncology Baotou Cancer Hospital Baotou China
- Youcai Zhu
- Department of Thoracic Disease Diagnosis and Treatment Center Zhejiang Rongjun Hospital, The Third Affiliated Hospital of Jiaxing University Jiaxing China
- Xiao Hu
- Zhejiang Key Laboratory of Radiation Oncology Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital) Hangzhou China
- Yanru Xie
- Department of Oncology Lishui Municipal Central Hospital Lishui China
- Xinqing Lin
- State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University (The First Affiliated Hospital of Guangzhou Medical University) Guangzhou China
- Jing Cai
- Department of Oncology Second Affiliated Hospital of Nanchang University Nanchang China
- Fen Lan
- Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine Second Affiliated Hospital of Zhejiang University School of Medicine, Cancer Center, Zhejiang University Hangzhou China
- Huijing Feng
- Department of Thoracic Oncology, Shanxi Academy of Medical Sciences Shanxi Bethune Hospital Taiyuan China
- Lin Wang
- Department of Pathology Shanxi Academy of Medical Sciences, Shanxi Bethune Hospital Taiyuan China
- Wang Yao
- Department of Interventional Oncology, The First Affiliated Hospital Sun Yat‐sen University Guangzhou China
- Xuefei Shi
- Department of Respiratory Medicine Huzhou Hospital, Zhejiang University School of Medicine Huzhou China
- Jianhui Huang
- Department of Oncology Lishui Municipal Central Hospital Lishui China
- Huafei Chen
- Department of Thoracic Disease Diagnosis and Treatment Center Zhejiang Rongjun Hospital, The Third Affiliated Hospital of Jiaxing University Jiaxing China
- Yinbin Zhang
- Department of Oncology, The Second Affiliated Hospital of Medical College Xi'an Jiaotong University Xi'an China
- Pingli Sun
- Department of Pathology The Second Hospital of Jilin University Changchun China
- Bing Wan
- Department of Respiratory Medicine The Affiliated Jiangning Hospital of Nanjing Medical University Nanjing China
- Fei Pang
- Department of Medical Shanghai OrigiMed Co. Ltd Shanghai China
- Zanmei Xu
- Department of Medical Shanghai OrigiMed Co. Ltd Shanghai China
- Kai Wang
- Department of Medical Shanghai OrigiMed Co. Ltd Shanghai China
- Yuanli Xia
- Department of Medical Affairs AstraZeneca China Shanghai China
- Mingxiang Ye
- Department of Respiratory Medicine Affiliated Jinling Hospital, Medical School of Nanjing University Nanjing China
- Dong Wang
- Department of Respiratory Medicine Affiliated Jinling Hospital, Medical School of Nanjing University Nanjing China
- Qing Wei
- Department of Chemotherapy Chinese Academy of Sciences University Cancer Hospital (Zhejiang Cancer Hospital) Hangzhou China
- Shuitu Feng
- Department of Oncology Xiamen Haicang Hospital Xiamen China
- Jianya Zhou
- Department of Respiratory Disease, Thoracic Disease Center, The First Affiliated Hospital, School of Medicine Zhejiang University Hangzhou China
- Jiexia Zhang
- State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University (The First Affiliated Hospital of Guangzhou Medical University) Guangzhou China
- Donglai Lv
- Department of Clinical Oncology The 901 Hospital of Joint Logistics Support Force of People Liberation Army Hefei China
- Wenbin Gao
- Department of Oncology The Third Affiliated Hospital of Shenzhen University Shenzhen China
- Jing Kang
- Guangdong Lung Cancer Institute, Guangdong Provincial Laboratory of Translational Medicine in Lung Cancer Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine Guangzhou China
- Genhua Yu
- Department of Radiation Oncology Zhebei Mingzhou Hospital Huzhou China
- Xianbin Liang
- Department of Oncology The Third People's Hospital of Zhengzhou Zhengzhou China
- Chengtao Yu
- Collaborative Innovation Center of Jiangsu Province of Cancer Prevention and Treatment of Chinese Medicine Nanjing China
- Lin Shi
- Department of Respiratory Medicine Zhongshan Hospital, Fudan University Shanghai China
- Nong Yang
- Department of Medical Oncology, Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University Changsha China
- Lin Wu
- Department of Medical Oncology, Lung Cancer, and Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University Changsha China
- Zhuan Hong
- Department of Medical Oncology Jiangsu Cancer Hospital, Nanjing Medical University Affiliated Cancer Hospital Nanjing China
- Wei Hong
- Department of Chemotherapy Chinese Academy of Sciences University Cancer Hospital (Zhejiang Cancer Hospital) Hangzhou China
- Meiyu Fang
- Department of Chemotherapy Chinese Academy of Sciences University Cancer Hospital (Zhejiang Cancer Hospital) Hangzhou China
- Yiping Zhang
- Department of Chemotherapy Chinese Academy of Sciences University Cancer Hospital (Zhejiang Cancer Hospital) Hangzhou China
- Yuanzhi Lu
- Department of Clinical Pathology The First Affiliated Hospital of Jinan University Guangzhou China
- Guansong Wang
- Institute of Respiratory Diseases Xinqiao Hospital, Third Military Medical University Chongqing China
- Shenglin Ma
- Department of Oncology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province Affiliated Hangzhou Cancer Hospital, Cancer Center, Zhejiang University School of Medicine Hangzhou China
- Lu Si
- Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Melanoma and Sarcoma Peking University Cancer Hospital and Institute Beijing China
- Wenfeng Fang
- Department of Medical Oncology Sun Yat‐sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Guangzhou China
- Yong Song
- Department of Respiratory Medicine Affiliated Jinling Hospital, Medical School of Nanjing University Nanjing China
- DOI
- https://doi.org/10.1111/1759-7714.14693
- Journal volume & issue
-
Vol. 13,
no. 23
pp. 3420 – 3430
Abstract
Abstract Immune checkpoint inhibitors (ICIs) have successfully treated a number of different types of cancer, which is of great significance for cancer treatment. With the widespread use of ICIs in clinical practice, the increasing checkpoint inhibitor pneumonia (CIP) will be a challenge to clinicians. To guide the diagnosis and treatment of CIP, we conducted in‐depth discussions based on the latest evidence, forming a consensus among Chinese experts on the multidisciplinary management of CIP.
Keywords
- checkpoint inhibitor pneumonitis
- Chinese experts consensus
- immune checkpoint inhibitor‐related adverse effects
