Journal of Clinical Medicine (Sep 2021)

Check the Need–Prevalence and Outcome after Transvenous Cardiac Implantable Electric Device Extraction without Reimplantation

  • Giuseppe D’Angelo,
  • David Zweiker,
  • Nicolai Fierro,
  • Alessandra Marzi,
  • Gabriele Paglino,
  • Simone Gulletta,
  • Mario Matta,
  • Francesco Melillo,
  • Caterina Bisceglia,
  • Luca Rosario Limite,
  • Manuela Cireddu,
  • Pasquale Vergara,
  • Francesco Bosica,
  • Giulio Falasconi,
  • Luigi Pannone,
  • Luigia Brugliera,
  • Teresa Oloriz,
  • Simone Sala,
  • Andrea Radinovic,
  • Francesca Baratto,
  • Lorenzo Malatino,
  • Giovanni Peretto,
  • Kenzaburo Nakajima,
  • Michael D. Spartalis,
  • Antonio Frontera,
  • Paolo Della Bella,
  • Patrizio Mazzone

DOI
https://doi.org/10.3390/jcm10184043
Journal volume & issue
Vol. 10, no. 18
p. 4043

Abstract

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Background: after transvenous lead extraction (TLE) of cardiac implantable electric devices (CIEDs), some patients may not benefit from device reimplantation. This study sought to analyse predictors and long-term outcome of patients after TLE with vs. without reimplantation in a high-volume centre. Methods: all patients undergoing TLE at our centre between January 2010 and November 2015 were included into this analysis. Results: a total of 223 patients (median age 70 years, 22.0% female) were included into the study. Cardiac resynchronization therapy-defibrillator (CRT-D) was the most common device (40.4%) followed by pacemaker (PM) (31.4%), implantable cardioverter-defibrillator (ICD) (26.9%), and cardiac resynchronization therapy-PM (CRT-P) (1.4%). TLE was performed due to infection (55.6%), malfunction (35.9%), system upgrade (6.7%) or other causes (1.8%). In 14.8%, no reimplantation was performed after TLE. At a median follow-up of 41 months, no preventable arrhythmia-related events were documented in the no-reimplantation group, but 11.8% received a new CIED after 17–84 months. While there was no difference in short-term survival, five-year survival was significantly lower in the no-reimplantation group (78.3% vs. 94.7%, p = 0.014). Conclusions: in patients undergoing TLE, a re-evaluation of the indication for reimplantation is safe and effective. Reimplantation was not related to preventable arrhythmia events, but all-cause survival was lower.

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