Effectiveness of onabotulinumtoxin A for refractory overactive bladder with cough‐associated detrusor overactivity

Abstract

Introduction We report a case of refractory overactive bladder with cough‐associated detrusor overactivity treated by onabotulinumtoxin A. Case presentation A 79‐year‐old woman who underwent mid‐urethral sling surgery 8 years ago complained mainly of urinary incontinence following abdominal pressure. Various medicines to treat overactive bladder symptoms were ineffective. Cystometry revealed cough‐associated detrusor overactivity. Onabotulinumtoxin A injections in her bladder improved subjective symptoms, and cough‐associated detrusor overactivity disappeared on cystometry. Conclusions Onabotulinumtoxin A injection effectively resolved refractory overactive bladder with urgency urinary incontinence due to cough‐associated detrusor overactivity.

Keywords

• cough‐associated detrusor overactivity
• onabotulinumtoxin A
• refractory overactive bladder
• urge urinary incontinence
• urodynamic study