Nature Communications (Sep 2019)

The molecular origin and taxonomy of mucinous ovarian carcinoma

  • Dane Cheasley,
  • Matthew J. Wakefield,
  • Georgina L. Ryland,
  • Prue E. Allan,
  • Kathryn Alsop,
  • Kaushalya C. Amarasinghe,
  • Sumitra Ananda,
  • Michael S. Anglesio,
  • George Au-Yeung,
  • Maret Böhm,
  • David D. L. Bowtell,
  • Alison Brand,
  • Georgia Chenevix-Trench,
  • Michael Christie,
  • Yoke-Eng Chiew,
  • Michael Churchman,
  • Anna DeFazio,
  • Renee Demeo,
  • Rhiannon Dudley,
  • Nicole Fairweather,
  • Clare G. Fedele,
  • Sian Fereday,
  • Stephen B. Fox,
  • C Blake Gilks,
  • Charlie Gourley,
  • Neville F. Hacker,
  • Alison M. Hadley,
  • Joy Hendley,
  • Gwo-Yaw Ho,
  • Siobhan Hughes,
  • David G. Hunstman,
  • Sally M. Hunter,
  • Tom W. Jobling,
  • Kimberly R. Kalli,
  • Scott H. Kaufmann,
  • Catherine J. Kennedy,
  • Martin Köbel,
  • Cecile Le Page,
  • Jason Li,
  • Richard Lupat,
  • Orla M. McNally,
  • Jessica N. McAlpine,
  • Anne-Marie Mes-Masson,
  • Linda Mileshkin,
  • Diane M. Provencher,
  • Jan Pyman,
  • Kurosh Rahimi,
  • Simone M. Rowley,
  • Carolina Salazar,
  • Goli Samimi,
  • Hugo Saunders,
  • Timothy Semple,
  • Ragwha Sharma,
  • Alice J. Sharpe,
  • Andrew N. Stephens,
  • Niko Thio,
  • Michelle C. Torres,
  • Nadia Traficante,
  • Zhongyue Xing,
  • Magnus Zethoven,
  • Yoland C. Antill,
  • Clare L. Scott,
  • Ian G. Campbell,
  • Kylie L. Gorringe

DOI
https://doi.org/10.1038/s41467-019-11862-x
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

Read online

Whether mucinous ovarian carcinoma (MOC) arises from cells at the ovary or from metastases from other primary sites is an unanswered question. Here, Cheasley et al perform a genetic analysis of the disease, showing that MOC arises at the ovary.