Nature Communications (Mar 2019)

Heterologous biosynthesis and characterization of a glycocin from a thermophilic bacterium

  • Arnoldas Kaunietis,
  • Andrius Buivydas,
  • Donaldas J. Čitavičius,
  • Oscar P. Kuipers

DOI
https://doi.org/10.1038/s41467-019-09065-5
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 12

Abstract

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Heterologous production of the glycocins, posttranslationally modified peptide bacteriocins containing a sugar moiety, has not been achieved. Here, the authors express a thermophilic bacterium glycocin biosynthetic gene cluster and S-glycosyltransferase for the production of antibacterial glycocins in E. coli.