Journal of Medical Case Reports (Nov 2008)

Bilateral dystonia in type 1 diabetes: a case report

  • Yasuhara Akihiro,
  • Wada Jun,
  • Makino Hirofumi

DOI
https://doi.org/10.1186/1752-1947-2-352
Journal volume & issue
Vol. 2, no. 1
p. 352

Abstract

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Abstract Introduction Diabetic hemichorea-hemiballismus is a rare complication of type 2 diabetes. Here, we report a case with type 1 diabetes, with hemichorea and bilateral dystonia manifested as hyperglycemia-induced involuntary movement. Case presentation A 62-year-old Japanese women with body weight loss of 30 kg during the past year developed symptoms of thirst, polydipsia and polyuria. She also presented with hemichorea and bilateral dystonia for 5 days and extremely high plasma glucose (774 mg/dl), hemoglobin A1c (21.2%) and glycated albumin (100%) with ketosis. Based on the presence of glutamic acid decarboxylase antibodies (18,000 U/ml; normal Conclusion Hyperglycemia-induced involuntary movement is one of the manifestations of dystonia and hemichorea-hemiballism.