Association of Mean Platelet Volume and Red Cell Distribution Width in Acute Ischemic Stroke

Abstract

Background: There is no surrogate biological marker for detecting stroke. Because of this, mean platelet volume (MPV) and RDW may be used to predict the occurrence of stroke. Aim: This study aims to see if there is a link between platelet volume and acute ischemic stroke, as well as between red cell distribution width and acute ischemic stroke. Setting and Design: This was a cross-sectional study from February 2021 to January 2023. Materials and Methods: The present cross-sectional study was conducted to assess the role of mean platelet volume and red cell distribution width in acute ischemic stroke. Statistical Analysis: For the analysis, SPSS version 20 was utilized. Results: A total of 300 patients were included in this study. The small vessel infarct (9.05 ± 1.24 fL) had less MPV than the large vessel infarct (9.10 ± 1.10 fL), but there was no statistically significant difference between the two (P = 0.74). The average red blood cell width was lower in minor stroke infarcts (15.06% ±2.01%) than in large stroke infarcts (15.5% ±7.26%), but no statistically significant difference was found in the study. Fifty-three (17.67%) patients had a deadly outcome, and 247 (82.33%) had been cured when a final diagnosis was made. Conclusions: Stroke is the world’s leading cause of mortality, caused by cerebral vascular blockage or hemorrhage. However, there is no biological substitute marker for stroke diagnosis. RDW and MPV are potential biomarkers for this function and can forecast the incidence of stroke.

Keywords

• acute ischemic stroke
• mean platelet volume
• red cell distribution width