Case Report: Pneumonia Caused by Chlamydia Psittaci and Cryptococcus Co-Infection

Abstract

Anbing Zhang,1,* Xiaoli Lao,1,2,* Jinguang Liang,3 Xiuqiong Xia,1 Lei Ma,4 Jianping Liang1,2 1Department of Respiratory and Critical Care Medicine, Zhongshan People’s Hospital, Zhongshan, People’s Republic of China; 2Guangdong Medical University, Zhanjiang, Guangdong, People’s Republic of China; 3Department of Respiratory and Critical Care Medicine, Zhongshan Huangpu People’s Hospital, Zhongshan, People’s Republic of China; 4Department of Respiratory and Critical Care Medicine, Fuyang Second People’s Hospital, Fuyang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jianping Liang, Department of Respiratory and Critical Care Medicine, Zhongshan People’s Hospital, No. 2, Sunwen East Road, Zhongshan, 528400, People’s Republic of China, Tel [phone], Fax [phone], Email [email protected]: This study presents a rare case of pneumonia caused by a co-infection of Chlamydia psittaci and Cryptococcus, confirmed by metagenomic next-generation sequencing (mNGS). The patient, who had underlying chronic hepatitis B, had adopted a stray pigeon before the onset of the disease. The primary symptoms were fever, and a productive cough. The patient recovered following treatment with moxifloxacin and itraconazole. C. psittaci and Cryptococcus infections may both have been transmitted from the stray pigeon. This report highlights the potential for infections caused by multiple zoonotic pathogens and the value of mNGS for making the diagnosis of these infections.Keywords: pneumonia, Chlamydia psittaci, Cryptococcus, co-infection, metagenomic next-generation sequencing

Keywords

• pneumonia
• chlamydia psittaci
• cryptococcus
• co-infection
• metagenomic next-generation sequencing