Proceedings (Mar 2024)

Noncoding Regulatory Mutations as a Driving Event for the Oncogenic Core Regulatory Circuitries of Neuroblastoma

  • Vincenzo Aievola,
  • Vito Alessandro Lasorsa,
  • Annalaura Montella,
  • Ferdinando Bonfiglio,
  • Marianna Avitabile,
  • Teresa Maiorino,
  • Matilde Tirelli,
  • Giuseppe D’Alterio,
  • Matthias Fischer,
  • Frank Westermann,
  • Achille Iolascon,
  • Mario Capasso

DOI
https://doi.org/10.3390/proceedings2024100018
Journal volume & issue
Vol. 100, no. 1
p. 18

Abstract

Read online

Neuroblastoma (NB) is a pediatric tumor composed of adrenergic (ADRN) and mesenchymal-like (MES) cells which derive from the dysregulation of normal cell differentiation imposed by NB Core Regulatory Circuitries (CRCs) [...]

Keywords