Nature Communications (Oct 2019)

Clinically relevant molecular subtypes and genomic alteration-independent differentiation in gynecologic carcinosarcoma

  • Osamu Gotoh,
  • Yuko Sugiyama,
  • Yutaka Takazawa,
  • Kazuyoshi Kato,
  • Norio Tanaka,
  • Kohei Omatsu,
  • Nobuhiro Takeshima,
  • Hidetaka Nomura,
  • Kosei Hasegawa,
  • Keiichi Fujiwara,
  • Mana Taki,
  • Noriomi Matsumura,
  • Tetsuo Noda,
  • Seiichi Mori

DOI
https://doi.org/10.1038/s41467-019-12985-x
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 14

Abstract

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Carcinosarcoma of the ovary or uterus comprises both carcinoma and sarcoma elements. Here, the authors perform a multi -omics study of the disease revealing therapeutic possibilities for this rare and aggressive disease.