NeuroSci (Feb 2022)

Neurocognitive Profiles of Caucasian Moyamoya Disease Patients in Greece: A Case Series

  • Georgios Papageorgiou,
  • Dimitrios Kasselimis,
  • Georgia Angelopoulou,
  • Dimitrios Tsolakopoulos,
  • Nikolaos Laskaris,
  • Argyro Tountopoulou,
  • Eleni Korompoki,
  • Georgios Velonakis,
  • Achilles Chatziioannou,
  • Konstantinos Spengos,
  • Constantin Potagas,
  • Sophia Vassilopoulou

DOI
https://doi.org/10.3390/neurosci3010010
Journal volume & issue
Vol. 3, no. 1
pp. 119 – 129

Abstract

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The impact of Moyamoya Disease (MMD) on cognition inadult Caucasian patients has not yet been thoroughly investigated. The current study is the first to present detailed neuropsychological data on a series of Greek patients with MMD. A group of eight patients was assessed with an extensive neuropsychological battery, including measures of episodic memory, working memory, executive functions, language, and social cognition. The results indicated that MMD may be characterized by a trichotomous neurocognitive profile, characterized by prominent impairment in working memory, executive functions, and social cognition. Overall, we stress the need for a thorough cognitive evaluation of MMD patients and further highlight the potential importance of social cognition in this particular disease. Possible associations between the three impaired cognitive domains in our group are also discussed.

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