Influence of pre-analytical sample preparation on drug concentration measurements in peritoneal tissue: an ex-vivo study

Affiliations

Castagna Arianna: Department of General, Visceral and Transplant Surgery, University of Tübingen, Tübingen, Germany
Sautkin Iaroslav: Department of General, Visceral and Transplant Surgery, University of Tübingen, Tübingen, Germany
Weinreich Frank-Jürgen: Department of General, Visceral and Transplant Surgery, University of Tübingen, Tübingen, Germany
Lee Hannah Heejung: Department of General, Visceral and Transplant Surgery, University of Tübingen, Tübingen, Germany
Königsrainer Alfred: Department of General, Visceral and Transplant Surgery, University of Tübingen, Tübingen, Germany
Reymond Marc André: Department of General, Visceral and Transplant Surgery, University of Tübingen, Tübingen, Germany
Nadiradze Giorgi: Department of General, Visceral and Transplant Surgery, University of Tübingen, Tübingen, Germany

Abstract

Biopsy morphology (surface/depth ratio) and sample processing might affect pharmacological measurements in peritoneal tissue.