Histopathological analysis of 177 cases with operated intracranial meningioma

Abstract

Purpose: Aim of this study is to evaluate histopathologic properties of patients with intracranial meningioma who were operated due to intracranial mass. Method: 177 cases diagnosed with intracranial meningioma were retrospectively examined in our clinic between the years of 2007-2012 and their age, sex, tumor localization, and histopathologic properties were analyzed. Results: 74.6% of 177 intracranial meningioma cases were females, 25.4% were males and the ratio of Male/Female was found 3.4/10. The age interval of the cases was between 12-105 years old. It was most frequently seen at the interval of 51-60. In histopathologic examination, 163 cases (92.1%) were noted as WHO Grade I, 11 cases (6.2%) were WHO Grade II, and 3 cases (1.7%) were WHO Grade III. While meningotelial transitional, and psammomatous type was the most frequently seen in WHO Grade I, atypical meningioma was only dominant in Grade II. In WHO Grade II and III cases, dominance of the male sex was present. While 88.1% of the cases had supratentorial localization, 11.9% had infratentorial localization, 1 case had lateral ventricle localization. In 7 cases (3.9%) of the series, multiple meningiomas were determined. Conclusion: In a series of 177 cases, intracranial meningiomas were seen between 51-60 years old and its most frequent localization was convexity. While Grade I cases were seen in the female sex, dominance of the male sex was present in Grade II and III cases. Additionally, all of multiple meningiomas detected were female cases. Meningotelial meningiomas constitute the most commonly seen subtype among Grade I cases. Key Words: Intracranial meningioma, histopathological classification, clinical study [Cukurova Med J 2013; 38(1.000): 41-59]

Keywords

• clinical analysis
• histopathological classification
• intracranial meningioma