Antibiotics (May 2023)
Six Long-Standing Questions about Antibiotic Prophylaxis in Surgery
- Massimo Sartelli,
- Marja A. Boermeester,
- Miguel Cainzos,
- Federico Coccolini,
- Stijn W. de Jonge,
- Kemal Rasa,
- E. Patchen Dellinger,
- Deborah A. McNamara,
- Donald E. Fry,
- Yunfeng Cui,
- Samir Delibegovic,
- Zaza Demetrashvili,
- Belinda De Simone,
- George Gkiokas,
- Timothy C. Hardcastle,
- Kamal M. F. Itani,
- Arda Isik,
- Francesco Maria Labricciosa,
- Varut Lohsiriwat,
- Sanjay Marwah,
- Tadeja Pintar,
- Jennifer Rickard,
- Vishal G. Shelat,
- Fausto Catena,
- Philip S. Barie
Affiliations
- Massimo Sartelli
- Department of Surgery, Macerata Hospital, 62100 Macerata, Italy
- Marja A. Boermeester
- Department of Surgery, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands
- Miguel Cainzos
- Department of Surgery, Hospital Clínico Universitario, 15706 Santiago de Compostela, Spain
- Federico Coccolini
- Department of Emergency and Trauma Surgery, Pisa University Hospital, University of Pisa, 55126 Pisa, Italy
- Stijn W. de Jonge
- Department of Surgery, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands
- Kemal Rasa
- Department of Surgery, Anadolu Medical Center, 41200 Kocaeli, Turkey
- E. Patchen Dellinger
- Department of Surgery, University of Washington, Seattle, WA 98195, USA
- Deborah A. McNamara
- Department of Colorectal Surgery, Beaumont Hospital, D09V2N0 Dublin, Ireland
- Donald E. Fry
- Department of Surgery, Northwestern University, Chicago, IL 60208, USA
- Yunfeng Cui
- Department of Surgery, Tianjin Nankai Hospital, Nankai Clinical School of Medicine, Tianjin Medical University, Tianjin 300100, China
- Samir Delibegovic
- Department of Surgery, University Clinical Center of Tuzla, 75000 Tuzla, Bosnia and Herzegovina
- Zaza Demetrashvili
- Department General Surgery, Kipshidze Central University Hospital, Tbilisi 0162, Georgia
- Belinda De Simone
- Department of Emergency and Metabolic Minimally Invasive Surgery, Centre Hospitalier Intercommunal de Poissy/Saint Germain en Laye, 78300 Poissy CEDEX, France
- George Gkiokas
- Second Department of Surgery, Aretaieion University Hospital, National and Kapodistrian University of Athens, 10679 Athens, Greece
- Timothy C. Hardcastle
- Department of Surgery, Nelson R. Mandela School of Clinical Medicine, University of KwaZulu-Natal, Mayville 4058, South Africa
- Kamal M. F. Itani
- Department of Surgery, VA Boston Health Care System, Boston University and Harvard Medical School, Boston, MA 02118, USA
- Arda Isik
- Division of General Surgery, School of Medicine, Istanbul Medeniyet University, 34700 Istanbul, Turkey
- Francesco Maria Labricciosa
- Global Alliance for Infections in Surgery, 62100 Macerata, Italy
- Varut Lohsiriwat
- Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
- Sanjay Marwah
- Department of Surgery, BDS Post-Graduate Institute of Medical Sciences, Rohtak 124001, India
- Tadeja Pintar
- Department of Abdominal Surgery, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia
- Jennifer Rickard
- Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA
- Vishal G. Shelat
- Department of Hepato-Pancreatic-Biliary Surgery, Tan Tok Seng Hospital, Singapore 308433, Singapore
- Fausto Catena
- Department of Surgery, “Bufalini” Hospital, 47023 Cesena, Italy
- Philip S. Barie
- Department of Surgery, Weill Cornell Medicine, E. Northport, New York, NY 11731, USA
- DOI
- https://doi.org/10.3390/antibiotics12050908
- Journal volume & issue
-
Vol. 12,
no. 5
p. 908
Abstract
Surgical site infections (SSIs) are the most common adverse event occurring in surgical patients. Optimal prevention of SSIs requires the bundled integration of a variety of measures before, during, and after surgery. Surgical antibiotic prophylaxis (SAP) is an effective measure for preventing SSIs. It aims to counteract the inevitable introduction of bacteria that colonize skin or mucosa into the surgical site during the intervention. This document aims to guide surgeons in appropriate administration of SAP by addressing six key questions. The expert panel identifies a list of principles in response to these questions that every surgeon around the world should always respect in administering SAP.
Keywords
