Repurposing Duloxetine as a Potent Butyrylcholinesterase Inhibitor: Potential Cholinergic Enhancing Benefits for Elderly Individuals with Depression and Cognitive Impairment

• Taher Darreh-Shori,
• Anurag T. K. Baidya,
• Medea Brouwer,
• Amit Kumar,
• Rajnish Kumar

Affiliations

Taher Darreh-Shori

Division of Clinical Geriatrics, Centre for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, NEO, Stockholm, Sweden

Anurag T. K. Baidya

Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (B.H.U.), Varanasi, Uttar Pradesh, India

Medea Brouwer

Division of Clinical Geriatrics, Centre for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, NEO, Stockholm, Sweden

Amit Kumar

Division of Clinical Geriatrics, Centre for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, NEO, Stockholm, Sweden

Rajnish Kumar

Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (B.H.U.), Varanasi, Uttar Pradesh, India