mBio
(Feb 2021)
Biogeography of the Relationship between the Child Gut Microbiome and Innate Immune System
Nelly Amenyogbe,
Pedro Dimitriu,
Kinga K. Smolen,
Eric M. Brown,
Casey P. Shannon,
Scott J. Tebbutt,
Phillip J. Cooper,
Arnaud Marchant,
Tessa Goetghebuer,
Monika Esser,
Brett B. Finlay,
Tobias R. Kollmann,
William W. Mohn
Affiliations
Nelly Amenyogbe
Department of Experimental Medicine, University of British Columbia, Vancouver, Canada
Pedro Dimitriu
Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, Canada
Kinga K. Smolen
Department of Experimental Medicine, University of British Columbia, Vancouver, Canada
Eric M. Brown
Michael Smith Laboratories, University of British Columbia, Vancouver, Canada
Casey P. Shannon
PROOF Centre of Excellence, St. Pauls’s Hospital, University of British Columbia, Vancouver, Canada
Scott J. Tebbutt
PROOF Centre of Excellence, St. Pauls’s Hospital, University of British Columbia, Vancouver, Canada
Phillip J. Cooper
Facultad de Ciencias Medicas, de la Salud y la Vida, Universidad Internacional del Ecuador, Quito, Ecuador
Arnaud Marchant
Institut d’Immunologie Médicale, Université Libre de Bruxelles, Charleroi, Belgium
Tessa Goetghebuer
Département de Pédiatrie, Centre Hospitalier Universitaire St Pierre, Université Libre de Bruxelles, Brussels, Belgium
Monika Esser
Immunology Unit, Division of Medical Microbiology, Department of Pathology, NHLS and Stellenbosch University, Matieland, Stellenbosch, South Africa
Brett B. Finlay
ORCiD Michael Smith Laboratories, University of British Columbia, Vancouver, Canada
Tobias R. Kollmann
Telethon Kids Institute, Perth, Australia
William W. Mohn
ORCiD Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, Canada
DOI
https://doi.org/10.1128/mBio.03079-20
Journal volume & issue
Vol. 12,
no. 1
Abstract
Read online
Both the gut microbiome and innate immunity are known to differ across biogeographically diverse human populations. The gut microbiome has been shown to directly influence systemic immunity in animal models.
WeChat QR code
Close
