Nature Communications (Nov 2018)

Quantifying post-transcriptional regulation in the development of Drosophila melanogaster

  • Kolja Becker,
  • Alina Bluhm,
  • Nuria Casas-Vila,
  • Nadja Dinges,
  • Mario Dejung,
  • Sergi Sayols,
  • Clemens Kreutz,
  • Jean-Yves Roignant,
  • Falk Butter,
  • Stefan Legewie

DOI
https://doi.org/10.1038/s41467-018-07455-9
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 14

Abstract

Read online

Proteome and transcriptome often show poor correlation, hindering the system-wide analysis of post-transcriptional regulation. Here, the authors study proteome and transcriptome dynamics during Drosophila embryogenesis and present basic mathematical models describing the temporal regulation of most protein-RNA pairs.