Oxidative Stress and Left Ventricular Performance in Patients with Different Glycometabolic Phenotypes

Abstract

The aim of the present study was to evaluate the possible correlation between oxidative stress and subclinical myocardial damage, assessed with speckle tracking echocardiography (STE), in normal glucose tolerance (NGT) patients with one-hour plasma glucose values ≥ 155 mg/dL (NGT ≥ 155), comparing them to NGT p p p p p p p = 0.001), but similar to IGT patients. Our study demonstrated that NGT ≥ 155 subjects exhibit early functional impairment of myocardial contractile fibres, these alterations are correlated with increased oxidative stress.

Keywords

• oxidative stress
• global longitudinal strain
• type 2 diabetes
• hyperglycaemia
• organ damage