Annals of Cardiac Anaesthesia (Jan 2014)

Correlation of cardiac output and sevoflurane required to maintain anesthetic depth targeted with entropy index

  • Andrei E Bautin,
  • Ann V Siganevich,
  • Elena Y Malaya,
  • Evgenii A Khomenko,
  • Mikhail L Gordeev,
  • Vladislav N Solntsev

DOI
https://doi.org/10.4103/0971-9784.124115
Journal volume & issue
Vol. 17, no. 1
pp. 4 – 7

Abstract

Read online

Aims and Objectives: We investigated the correlation of reduced cardiac output on required sevoflurane to maintain targeted anesthesia depth. Materials and Methods: 36 patients undergoing coronary artery bypass grafting with cardiopulmonary bypass were prospectively included in the study. Inspired sevoflurane concentration was adjusted to ensure state entropy index 2.2 l/min/m 2 (1.37% ± 0.31%), P = 0.01. Conclusion: Relationship between CI and ETsev required for maintaining target level of anesthesia is non-linear. Patients with CI ≤ 2.2 l/min/m 2 need lower levels of the ETsev for maintenance of the target anesthesia at an entropy index < 40.

Keywords