Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders

• Elisa M. Crombie,
• Andrea J. Korecki,
• Karen Cleverley,
• Bethany A. Adair,
• Thomas J. Cunningham,
• Weaverly Colleen Lee,
• Tess C. Lengyell,
• Cheryl Maduro,
• Victor Mo,
• Liam M. Slade,
• Ines Zouhair,
• Elizabeth M. C. Fisher,
• Elizabeth M. Simpson

Affiliations

Elisa M. Crombie

Department of Neuromuscular Diseases, UCL Institute of Neurology, University College London, London WC1N 3BG, UK

Andrea J. Korecki

Centre for Molecular Medicine and Therapeutics at BC Children's Hospital, University of British Columbia, Vancouver, BC V5Z 4H4, Canada

Karen Cleverley

Department of Neuromuscular Diseases, UCL Institute of Neurology, University College London, London WC1N 3BG, UK

Bethany A. Adair

Centre for Molecular Medicine and Therapeutics at BC Children's Hospital, University of British Columbia, Vancouver, BC V5Z 4H4, Canada

Thomas J. Cunningham

MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK

Weaverly Colleen Lee

Department of Neuromuscular Diseases, UCL Institute of Neurology, University College London, London WC1N 3BG, UK

Tess C. Lengyell

Centre for Molecular Medicine and Therapeutics at BC Children's Hospital, University of British Columbia, Vancouver, BC V5Z 4H4, Canada

Cheryl Maduro

Department of Neuromuscular Diseases, UCL Institute of Neurology, University College London, London WC1N 3BG, UK

Victor Mo

Centre for Molecular Medicine and Therapeutics at BC Children's Hospital, University of British Columbia, Vancouver, BC V5Z 4H4, Canada

Liam M. Slade

Centre for Molecular Medicine and Therapeutics at BC Children's Hospital, University of British Columbia, Vancouver, BC V5Z 4H4, Canada

Ines Zouhair

Department of Neuromuscular Diseases, UCL Institute of Neurology, University College London, London WC1N 3BG, UK

Elizabeth M. C. Fisher

Department of Neuromuscular Diseases, UCL Institute of Neurology, University College London, London WC1N 3BG, UK

Elizabeth M. Simpson

Centre for Molecular Medicine and Therapeutics at BC Children's Hospital, University of British Columbia, Vancouver, BC V5Z 4H4, Canada