Two New Monoterpenes from the Fruits of Illicium lanceolatum

Abstract

Two new monoterpenes, p-mentha-1(7),8-dien-2-O-b-d-glucoside (1) and trans-2,4-dihydroxy-2,4-dimethyl-trans-1-acetic acid g-lactone (2) were isolated from the fruits of Illicium lanceolatum along with trans-2,4-dihydroxy-2,4-dimethyl-cis-1-acetic acid g-lactone (3), (1R,2R,4R)-8-p-menthen-1,2-diol (4), trans-sobrerol (5), (1S,2S,4R)-p-menthane-1,2,8-triol (6) and (1S, 2S, 4R, 8R)-p-menthane-1,2,9-triol (7). The structures of the isolates were confirmed by spectroscopic analysis and they showed no inhibitory effects on the in vitro growth of microbial organisms (Escherichia coli, Staphyloccocus aureus, Bacillus subtilis) at less than 1.0 mg/mL.

Keywords

• Illicium lanceolatum
• monoterpenes
• anti-microbial activity